Unless you haul for total victory in the Endgame, the type of goods assigned in every set has a big influence on the final result.
This EG on SoE i see Megacities who have 3 one track RGs assigned in the first set of 12, and my Megacity has no 1 or 2 tracks RGs assigned, an other Megacity has five Era6 goods (5/6/7 tracks) assigned. The assigned goods can make the difference between ending 3rd or 10th, and that is not fair.
In order to make it more fair and balanced:
Make the assignment of RGs equal for all Megacities, so all has the same chance for a good result.
Equal could be:
1) each set of 12 consists out of 2 RGs from each Era
2) equal number of tracks
The element of LUCK in the assigned RGs has a too big influence on the result.