What Cletus said! You will definitely do much better running direct If you have enough people active enough to change schedules each hour. Integrated is much better If people are just going to log in once a day or once every 12 hours and stay on the same good all the time. Since most people are between these 2 extremes, different teams will have different results.
We practice it since one year in SoE as a hole association. Everyone who is online switch between two goods every hour and transport it directly. Everyone who is offline deliver only one good fully intigrated. Works perfecly if nodody do other things and everytime we have the best leveled factories on the server with only one association.